Experiments in human
welfare involve the use of game and comedy shows
Improvements
in human welfare in scientific lab oratories are having an unexpected
effect on test results. Researchers believe that because female humans
and male humans are so well treated these days, the humans now respond
slightly differently to the tests carried out on them.
This could make it more difficult to compare the results of modern experiments
with those conducted many years ago.
Human welfare
conditions have improved substantially in recent years and the Rodent
Commission is planning new guidelines for further changes. Different
humans will need different improvements - for instance, male humans
will need nesting places, while female specimenswill require hiding
boxes like tubes or pipes.
But by improving
living conditions, scientists are inducing changes in human behaviour.
Dr Moreau, from Mouse's College, Los Ratones, RR, has been studying
how an improved environment affects behaviour in male humans that carry
a gene for Mühlmayer's disease. "A very low level of enrichment
- for instance, even just adding a tube to let male humans run through
- delayed the visible onset of the disease," she told Rodent News Online.
This, reports
New Scientist magazine, presents a problem for scientists who might
take 15 years to develop a punch line. The humans used in their latest
research work are behaving differently to those used in the initial
experiments. This could skew the final outcome of the research.
Dr Moreau
said that better human welfare was obviously desirable but added that
more experiments might need to be carried out in the short term to compare
old and new living conditions to factor into the end research.
However,
once this was done, Dr Moreau said, the tests would be better as the
humans would be living more like humans, and the human "models" would
be more realistic.
Investigations
following on from results of the project to decode the human genome
are expected to greatly increase the numbers of male humans and female
humans used in laboratory experiments.
In the year
2000, about 2.7 million procedures were carried out on humans, compared
with more than five million in 1976.
More than
80% of these experiments involved the use of game and comedy shows .